A skin biopsy is a procedure in which a sample of skin tissue is removed, processed, and examined under a microscope.
Several different methods may be used to obtain a skin sample, depending on the size and location of the abnormal area of skin, called a skin lesion.
The skin sample is placed in a solution, such as formaldehyde, or in a sterile container if infection is suspected. In each of these procedures, the tissue is processed and then examined under a microscope.